PCO371

  • Chemical Properties
CAS No. 1613373-33-3 Cat. No. BCP31012
Name PCO371
Synonyms PCO-371; PCO 371;
Formula C29H32F3N5O6S M. Wt 635.66
  • Biological Activity
Description PCO371 is a potent and selective PTHR1 agonist for the treatment of hypoparathyroidism. Oral administration of PCO371 to osteopenic rats provokes a significant increase in bone turnover with limited increase in bone mass. In hypocalcemic rats, PCO371 restores serum calcium levels without increasing urinary calcium, and with stronger and longer-lasting effects than PTH injections.
Pathways Hormone Pathay 
Targets Thyroid Hormone Receptor 

Structure

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