PCO371 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1613373-33-3 | Cat. No. | BCP31012 |
| Name | PCO371 | ||
| Synonyms | PCO-371; PCO 371; | ||
| SMILES | CC1=CC(=CC(=C1CCS(=O)(=O)N2CCC3(CC2)C(=O)NC(=N3)C4=CC=C(C=C4)OC(F)(F)F)C)N5C(=O)NC(=O)C5(C)C | ||
| Chemical Name | |||
| Formula | C29H32F3N5O6S | M. Wt | 635.66 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PCO371 is a potent and selective PTHR1 agonist for the treatment of hypoparathyroidism. Oral administration of PCO371 to osteopenic rats provokes a significant increase in bone turnover with limited increase in bone mass. In hypocalcemic rats, PCO371 restores serum calcium levels without increasing urinary calcium, and with stronger and longer-lasting effects than PTH injections. | ||
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