JI051

  • Chemical Properties
CAS No. 2234281-75-3 Cat. No. BCP31018
Name JI051
Synonyms JI-051; JI 051;
Formula C22H24N2O3 M. Wt 364.45
  • Biological Activity
Description JI051 is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity.
Pathways Wnt/Stem Cell 
Targets Notch 

Structure

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