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CAS No. | 2234281-75-3 | Cat. No. | BCP31018 |
Name | JI051 | ||
Synonyms | JI-051; JI 051; | ||
SMILES | CCOC1=CC=CC=C1CCNC(=O)C=CC2=CNC3=C2C=CC=C3OC | ||
Chemical Name | |||
Formula | C22H24N2O3 | M. Wt | 364.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | JI051 is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity. |
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