INH14
| CAS No. | 200134-22-1 | Cat. No. | BCP31056 |
| Name | INH14 | ||
| Synonyms | INH 14; INH-14; | ||
| Formula | C15H16N2O | M. Wt | 240.31 |
| Description | INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity. | ||
| Pathways | NFκB | ||
| Targets | IκB/IKK | ||
Structure
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