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CAS No. | 200134-22-1 | Cat. No. | BCP31056 |
Name | INH14 | ||
Synonyms | INH 14; INH-14; | ||
SMILES | O=C(NC1=CC=CC=C1)NC2=CC=C(CC)C=C2 | ||
Chemical Name | |||
Formula | C15H16N2O | M. Wt | 240.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity. |
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