JG98

  • Chemical Properties
CAS No. 1456551-16-8 Cat. No. BCP31061
Name JG98
Synonyms JG 98;JG-98;
Formula C24H21Cl2N3OS3 M. Wt 534.54
  • Biological Activity
Description JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
Pathways Protease/Metabolic Enzyme Cell Cycle/DNA Damage 
Targets HSP 

Structure

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