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JG98 Chemical Structure

JG98

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31061CAS No. :1456551-16-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1456551-16-8 Cat. No. BCP31061
Name JG98
Synonyms JG 98;JG-98;
SMILES CCN1C(=CC2=[N+](C=CS2)CC3=CC=CC=C3)SC(=C4N(C5=C(S4)C=C(C=C5)Cl)C)C1=O.[Cl-]
Chemical Name
Formula C24H21Cl2N3OS3 M. Wt 534.54
Purity 98% Storage Store at 4-8°C
Description JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
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