Bobcat339
| CAS No. | 2280037-51-4 | Cat. No. | BCP31159 |
| Name | Bobcat339 | ||
| Synonyms | Bobcat-339; Bobcat 339; | ||
| Formula | C16H12ClN3O | M. Wt | 297.74 |
| Description | Bobcat339 is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2). Bobcat339 has mid-μM inhibitor activity against TET1 and TET2, but does not inhibit the DNA methyltransferase, DNMT3a. These new molecular tools will be useful to the field of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription. | ||
| Pathways | Others Pathway Epigenetics | ||
| Targets | DNA Methyltransferase Others | ||
Structure
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