Bobcat339 New
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CAS No. | 2280037-51-4 | Cat. No. | BCP31159 |
Name | Bobcat339 | ||
Synonyms | Bobcat-339; Bobcat 339; | ||
SMILES | O=C1N=C(N)C(Cl)=CN1C2=CC(C3=CC=CC=C3)=CC=C2 | ||
Chemical Name | |||
Formula | C16H12ClN3O | M. Wt | 297.74 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Bobcat339 is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2). Bobcat339 has mid-μM inhibitor activity against TET1 and TET2, but does not inhibit the DNA methyltransferase, DNMT3a. These new molecular tools will be useful to the field of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription. |
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