孕烷醇酮
| CAS号 | 128-20-1 | 货号 | BCP31318 |
| 中文名 | 孕烷醇酮 | ||
| 英文名 | Pregnanolone | ||
| 中文别名 | 3α-羟基-5β-孕(甾)烷-20-酮;5α-孕(甾)烷-3β-醇-20-酮; 乙他诺隆; | ||
| 英文别名 | Eltanolone; Kabi-2213; Kabi 2213; Kabi2213; SKF 6455; SKF6455;3a5b-Pregnanolone; | ||
| 分子式 | C21H34O2 | 分子量 | 318.49 |
| 生物活性 | Pregnanolone is a cell membrane modulator potentially for the treatment of pain. Pregnanolone is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects. It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for that reason was never marketed. | ||
| 信号通路 | Hormone Pathay | ||
| 靶 点 | Progesterone Receptor | ||
结构式
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