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CAS号 | 128-20-1 | 货号 | BCP31318 |
中文名 | 孕烷醇酮 | ||
英文名 | Pregnanolone | ||
中文别名 | 3α-羟基-5β-孕(甾)烷-20-酮;5α-孕(甾)烷-3β-醇-20-酮; 乙他诺隆; | ||
英文别名 | Eltanolone; Kabi-2213; Kabi 2213; Kabi2213; SKF 6455; SKF6455;3a5b-Pregnanolone; | ||
SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C | ||
化学名称 | |||
分子式 | C21H34O2 | 分子量 | 318.49 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Pregnanolone is a cell membrane modulator potentially for the treatment of pain. Pregnanolone is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects. It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for that reason was never marketed. |
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