LM10
| CAS No. | 1316695-35-8 | Cat. No. | BCP31973 |
| Name | LM10 | ||
| Synonyms | LM 10; LM-10; | ||
| Formula | C11H8FN5 | M. Wt | 229.22 |
| Description | LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). LM10 exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. LM10 reduces growth of TDO-expressing P815 mastocytoma tumors in mice. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | IDO | ||
Structure
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