EC-5026
| CAS No. | 1809885-32-2 | Cat. No. | BCP31997 |
| Name | EC-5026 | ||
| Synonyms | EC 5026; EC5026; BPN-19186; BPN 19186; BPN19186; | ||
| Formula | C18H23F4N3O3 | M. Wt | 405.39 |
| Description | EC5026 is a first-in-class, potent and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 acts on the cytochrome P450 branch of the arachidonate cascade to stabilize epoxides of polyunsaturated fatty acids (EpFA), which are natural mediators that reduce pain, resolve inflammation, and maintain normal blood pressure. EC5026 is a slow-tight binding transition-state mimic that inhibits the soluble epoxide hydrolase (sEH) at picomolar concentrations. | ||
| Pathways | Protease/Metabolic Enzyme | ||
Structure
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