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EC-5026 Chemical Structure

EC-5026

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31997CAS No. :1809885-32-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1809885-32-2 Cat. No. BCP31997
Name EC-5026
Synonyms EC 5026; EC5026; BPN-19186; BPN 19186; BPN19186;
SMILES CC[C@H](C)C(=O)N1CCC(CC1)NC(=O)NC2=CC(=C(C=C2)OC(F)(F)F)F
Chemical Name
Formula C18H23F4N3O3 M. Wt 405.39
Purity 98% Storage Store at 4-8°C
Description EC5026 is a first-in-class, potent and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 acts on the cytochrome P450 branch of the arachidonate cascade to stabilize epoxides of polyunsaturated fatty acids (EpFA), which are natural mediators that reduce pain, resolve inflammation, and maintain normal blood pressure. EC5026 is a slow-tight binding transition-state mimic that inhibits the soluble epoxide hydrolase (sEH) at picomolar concentrations.
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