ASTX-029
| CAS号 | 2095719-92-7 | 货号 | BCP32082 |
| 中文名 | ASTX-029 | ||
| 英文名 | ASTX-029 | ||
| 中文别名 | |||
| 英文别名 | ASTX 029;ASTX 029;ERK1/2 inhibitor 2; | ||
| 分子式 | C29H31ClFN5O5 | 分子量 | 584.04 |
| 生物活性 | ASTX029 is a synthetic small molecule inhibitor of extracellular signal-regulated kinases (ERKs) 1/2. ASTX029 has not been previously evaluated in human subjects. The Phase 1 portion of this study will assess safety and determine the maximum tolerated dose, the recommended Phase 2 dose (RP2D), and the recommended dosing regimen of ASTX029 administered orally. The Phase 2 portion will assess preliminary clinical activity in tumors characterized by gene aberrations in the mitogen-activated protein kinase (MAPK) signal pathway that may confer sensitivity to ASTX029. | ||
| 信号通路 | MAPK Pathway | ||
| 靶 点 | MEK/ERK | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！