Anle138b
CAS号 | 882697-00-9 | 货号 | BCP32558 |
中文名 | Anle138b | ||
英文名 | Anle138b | ||
中文别名 | |||
英文别名 | Anle 138b; Anle-138b; | ||
分子式 | C16H11BrN2O2 | 分子量 | 343.17 |
生物活性 | Anle138b is a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.. Anle138b blocks the activity of conducting Aβ pores without changing the membrane embedded Aβ-oligomer structure, at the mechanistic level. Anle138b blocks interpeptide main chain interactions and impedes the spontaneous formation of ordered β-sheet structures, in particular those with out-of-register antiparallel β-strands. | ||
信号通路 | Others Pathway | ||
靶 点 | Others |
结构式

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