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CAS号 | 882697-00-9 | 货号 | BCP32558 |
中文名 | Anle138b | ||
英文名 | Anle138b | ||
中文别名 | |||
英文别名 | Anle 138b; Anle-138b; | ||
SMILES | C1OC2=C(O1)C=C(C=C2)C3=CC(=NN3)C4=CC(=CC=C4)Br | ||
化学名称 | |||
分子式 | C16H11BrN2O2 | 分子量 | 343.17 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Anle138b is a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.. Anle138b blocks the activity of conducting Aβ pores without changing the membrane embedded Aβ-oligomer structure, at the mechanistic level. Anle138b blocks interpeptide main chain interactions and impedes the spontaneous formation of ordered β-sheet structures, in particular those with out-of-register antiparallel β-strands. |
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