Longdaysin
| CAS No. | 1353867-91-0 | Cat. No. | BCP32583 |
| Name | Longdaysin | ||
| Synonyms | |||
| Formula | C16H16F3N5 | M. Wt | 335.33 |
| Description | Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. Longdaysin inhibits CK1α, CK1δ, CDK7, and ERK2 with IC50s of 5.6 µM, 8.8 µM, 29 µM, and 52 µM, respectively. | ||
| Pathways | Cell Cycle/DNA Damage Wnt/Stem Cell MAPK Pathway | ||
| Targets | Casein Kinase MEK/ERK CDK | ||
Structure
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