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CAS No. | 1353867-91-0 | Cat. No. | BCP32583 |
Name | Longdaysin | ||
Synonyms | |||
SMILES | CC(C)N1C=NC2=C(N=CN=C21)NCC3=CC(=CC=C3)C(F)(F)F | ||
Chemical Name | |||
Formula | C16H16F3N5 | M. Wt | 335.33 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. Longdaysin inhibits CK1α, CK1δ, CDK7, and ERK2 with IC50s of 5.6 µM, 8.8 µM, 29 µM, and 52 µM, respectively. |
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