Selinexor E-isomer
| CAS No. | 1421923-86-5 | Cat. No. | BCP32614 |
| Name | Selinexor E-isomer | ||
| Synonyms | Selinexor trans-isomer;KPT-330, (E)-;KPT-330 E-isomer; KPT330 trans isomer; E-KPT 330; | ||
| Formula | C17H11F6N7O | M. Wt | 443.31 |
| Description | Selinexor trans-isomer is a trans-isomer of Selinexor or KPT-330, which is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CRM1 | ||
Structure
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