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CAS No. | 1421923-86-5 | Cat. No. | BCP32614 |
Name | Selinexor E-isomer | ||
Synonyms | Selinexor trans-isomer;KPT-330, (E)-;KPT-330 E-isomer; KPT330 trans isomer; E-KPT 330; | ||
SMILES | C1=CN=C(C=N1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F | ||
Chemical Name | |||
Formula | C17H11F6N7O | M. Wt | 443.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Selinexor trans-isomer is a trans-isomer of Selinexor or KPT-330, which is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. |
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