MD2-TLR4-IN-1

  • Chemical Properties
CAS No. 2249801-12-3 Cat. No. BCP32678
Name MD2-TLR4-IN-1
Synonyms
Formula C22H14Cl2N4O M. Wt 421.28
  • Biological Activity
Description MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively.
Pathways Others Pathway 
Targets TLR 

Structure

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