MD2-TLR4-IN-1 New
Data Sheet
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| CAS No. | 2249801-12-3 | Cat. No. | BCP32678 |
| Name | MD2-TLR4-IN-1 | ||
| Synonyms | |||
| SMILES | ClC1=C(C(NC2=CC(C(C3=CC=C(NC=C4)C4=C3)=NN5)=C5C=C2)=O)C(Cl)=CC=C1 | ||
| Chemical Name | |||
| Formula | C22H14Cl2N4O | M. Wt | 421.28 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. | ||
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