CC-92480
| CAS No. | 2259648-80-9 | Cat. No. | BCP32805 |
| Name | CC-92480 | ||
| Synonyms | CC 92480; CC92480; | ||
| Formula | C32H30FN5O4 | M. Wt | 567.62 |
| Description | CC-92480 is a cereblon E3 ubiquitin ligase modulating agent with potential immunomodulating and antineoplastic activities. CC-92480 specifically binds to cereblon (CRBN), thereby affecting the ubiquitin E3 ligase activity, and targeting certain substrate proteins for ubiquitination. This induces proteasome-mediated degradation of certain transcription factors, some of which are transcriptional repressors in T cells. This leads to modulation of the immune system, including activation of T lymphocytes, and downregulation of the activity of other proteins, some of which play key roles in the proliferation of certain cancer cell types. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | E1 E2 E3 Enzyme | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.