SIB 1757
| CAS No. | 31993-01-8 | Cat. No. | BCP33033 |
| Name | SIB 1757 | ||
| Synonyms | SIB-1757; SIB1757; | ||
| Formula | C12H11N3O | M. Wt | 213.24 |
| Description | SIB-1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. SIB-1757 displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mGluR | ||
Structure
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