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CAS No. | 31993-01-8 | Cat. No. | BCP33033 |
Name | SIB 1757 | ||
Synonyms | SIB-1757; SIB1757; | ||
SMILES | CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2 | ||
Chemical Name | |||
Formula | C12H11N3O | M. Wt | 213.24 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SIB-1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. SIB-1757 displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8. |
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