YM 298198 Hydrochloride
| CAS No. | 748758-45-4 | Cat. No. | BCP33084 |
| Name | YM 298198 Hydrochloride | ||
| Synonyms | YM 298198 HCl; YM298198 HCl; YM-298198 HCl; | ||
| Formula | C18H23ClN4OS | M. Wt | 378.92 |
| Description | YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). YM 298198 Hydrochloride is inactive at other mGlu receptor subtypes (mGlu2-7), ionotropic receptors and glutamate transporters (IC50 > 10 μM). It inhibits glutamate-induced IP production more potently than CPCCOEt (IC50 values are 16 nM and 6.3 μM respectively). | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mGluR | ||
Structure
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