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YM 298198 Hydrochloride Chemical Structure

YM 298198 Hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33084CAS No. :748758-45-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 748758-45-4 Cat. No. BCP33084
Name YM 298198 Hydrochloride
Synonyms YM 298198 HCl; YM298198 HCl; YM-298198 HCl;
SMILES CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4
Chemical Name
Formula C18H23ClN4OS M. Wt 378.92
Purity 98% Storage Store at 4-8°C
Description YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). YM 298198 Hydrochloride is inactive at other mGlu receptor subtypes (mGlu2-7), ionotropic receptors and glutamate transporters (IC50 > 10 μM). It inhibits glutamate-induced IP production more potently than CPCCOEt (IC50 values are 16 nM and 6.3 μM respectively).
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