Edonerpic maleate

  • Chemical Properties
CAS No. 519187-97-4 Cat. No. BCP33233
Name Edonerpic maleate
Synonyms T-817 maleate; T-817MA;T817 maleate; T817MA;T 817 maleate; T 817MA;
Formula C20H25NO6S M. Wt 407.48
  • Biological Activity
Description Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Edonerpic, also known as T-817, is a neuroprotectant. Edonerpic is a candidate therapeutic agent for Alzheimer's disease that inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor. Edonerpic protects against MPTP-induced neurotoxicity by blocking lipid peroxidation in the SNc, and imply that this compound may be useful for treating neurodegenerative disorders related to oxidative stress, such as Parkinson's disease.
Pathways Neuro Signaling Pathway 
Targets Amyloid β 

Structure

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