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Amyloid β

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Amyloid β

Chemical Structure Cat. No. Product Name CAS No.
UB-311 Chemical Structure
 BCP49318 UB-311 UB-311
UB-311 is an anti–amyloid-β active immunotherapeutic vaccine shown to be well-tolerated and to have a durable antibody response in a phase 1 trial.
THK-523 Chemical Structure
 BCP24740 THK-523 1354653-91-0
THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo.
beta-Cyclodextrin, 2-hydroxypropyl ethers Chemical Structure
 BCP25350 beta-Cyclodextrin, 2-hydroxypropyl ethers 128446-35-5
2-Hydroxypropyl-b-cyclodextrinis a β-cyclodextrin derivative with enhanced water solubility.
Tabersonine Chemical Structure
 BCP48228 Tabersonine 4429-63-4
Tabersonine is an inhibitor of Amyloid Fibril Formation and Cytotoxicity of Aβ(1-42) that is able to permeate the blood-brain barrier.
Begacestat Chemical Structure
 BCP46406 Begacestat 769169-27-9
Begacestat is a selective thiophene sulfonamide amyloid precursor protein gamma-secretase inhibitor (Aβ40,IC50=15 nM),and for the treatment of Alzheimer's disease.
PBD-150 Chemical Structure
 BCP44463 PBD-150 790663-33-1
PBD-150 is a potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM.
Colivelin Chemical Structure
 BCP42673 Colivelin 867021-83-8
Colivelin is a brain-penetrant neuroprotective peptide with potent long-term capacity against Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease. Colivelin is an activator of STAT3.
ALZ801 Chemical Structure
 BCP41130 ALZ801 1034190-08-3
ALZ801 is an oral, small-molecule inhibitor of beta amyloid (Aβ) oligomer formation for Alzheimer's disease (AD).
TAE-1 Chemical Structure
 BCP37827 TAE-1 1414469-59-2
TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation, suggesting its potential for the treatment of Alzheimer′s disease.
Cranad 2 Chemical Structure
 BCP25913 Cranad 2 1193447-34-5
Cranad 2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.
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