Mobocertinib succinate
CAS No. | 2389149-74-8 | Cat. No. | BCP33315 |
Name | Mobocertinib succinate | ||
Synonyms | TAK-788 succinate; AP32788 succinate;TAK 788 succinate; AP 32788 succinate;TAK788 succinate; AP-32788 succinate; | ||
Formula | C36H45N7O8 | M. Wt | 703.78 |
Description | Mobocertinib succinate is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
Targets | EGFR HER2 |
Structure
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