Mobocertinib succinate New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2389149-74-8 | Cat. No. | BCP33315 |
| Name | Mobocertinib succinate | ||
| Synonyms | TAK-788 succinate; AP32788 succinate;TAK 788 succinate; AP 32788 succinate;TAK788 succinate; AP-32788 succinate; | ||
| SMILES | O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C.O=C(O)CCC(O)=O | ||
| Chemical Name | |||
| Formula | C36H45N7O8 | M. Wt | 703.78 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Mobocertinib succinate is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs. | ||
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