Evocalcet
| CAS No. | 870964-67-3 | Cat. No. | BCP33803 |
| Name | Evocalcet | ||
| Synonyms | MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; | ||
| Formula | C24H26N2O2 | M. Wt | 374.48 |
| Description | Evocalcet is a calcium-sensing receptor agonist. The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ion. The calcium-sensing receptor controls calcium homeostasis by regulating the release of parathyroid hormone (PTH). CaSR is expressed in all of the organs of the digestive system. CaSR plays a key role in gastrointestinal physiological function and in the occurrence of digestive disease. High dietary Ca2+ may stimulate CaSR activation and could both inhibit tumor development and increase the chemotherapeutic sensitivity of cancer cells in colon cancer tissues. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CaSR | ||
Structure
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