Evocalcet New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP33803CAS No. ：870964-67-3Purity：98%

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CAS No.	870964-67-3	Cat. No.	BCP33803
Name	Evocalcet
Synonyms	MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580;
SMILES	CC(C1=CC=CC2=CC=CC=C21)NC3CCN(C3)C4=CC=C(C=C4)CC(=O)O
Chemical Name
Formula	C24H26N2O2	M. Wt	374.48
Purity	98%	Storage	Store at 4-8°C
Description	Evocalcet is a calcium-sensing receptor agonist. The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ion. The calcium-sensing receptor controls calcium homeostasis by regulating the release of parathyroid hormone (PTH). CaSR is expressed in all of the organs of the digestive system. CaSR plays a key role in gastrointestinal physiological function and in the occurrence of digestive disease. High dietary Ca2+ may stimulate CaSR activation and could both inhibit tumor development and increase the chemotherapeutic sensitivity of cancer cells in colon cancer tissues.