DSR-141562
| CAS No. | 2007975-22-4 | Cat. No. | BCP34050 |
| Name | DSR-141562 | ||
| Synonyms | DSR141562;DSR 141562; | ||
| Formula | C19H25F3N4O3 | M. Wt | 414.42 |
| Description | DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphodiesterase/PDE | ||
Structure
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