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CAS No. | 2007975-22-4 | Cat. No. | BCP34050 |
Name | DSR-141562 | ||
Synonyms | DSR141562;DSR 141562; | ||
SMILES | CN1C(=O)C2=CN=C(N2N=C1OCC3CCC(CC3)C(F)(F)F)C4CCOCC4 | ||
Chemical Name | |||
Formula | C19H25F3N4O3 | M. Wt | 414.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia. |
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