MYCi361

  • Chemical Properties
CAS No. 2289690-31-7 Cat. No. BCP34061
Name MYCi361
Synonyms MYCi-361;MYCi 361;NUCC-0196361;NUCC 0196361;NUCC0196361;
Formula C26H16ClF9N2O2 M. Wt 594.86
  • Biological Activity
Description MYCi361 is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy.MYCi361 inhibits the viability of MYC-dependent cancer cells including prostate cancer (MycCaP, LNCaP, and PC3), leukemia (MV4-11), lymphoma (HL-60 and P493-6), and neuroblastoma (SK-N-B2) with low-micromolar IC50 values.
Pathways Apoptosis Pathway 
Targets c Myc 

Structure

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