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MYCi361 Chemical Structure

MYCi361

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34061CAS No. :2289690-31-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2289690-31-7 Cat. No. BCP34061
Name MYCi361
Synonyms MYCi-361;MYCi 361;NUCC-0196361;NUCC 0196361;NUCC0196361;
SMILES CN1C(=CC(=N1)C(F)(F)F)C2=C(C(=C(C=C2)OCC3=CC=C(C=C3)Cl)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)O
Chemical Name
Formula C26H16ClF9N2O2 M. Wt 594.86
Purity 98% Storage Store at 4-8°C
Description MYCi361 is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy.MYCi361 inhibits the viability of MYC-dependent cancer cells including prostate cancer (MycCaP, LNCaP, and PC3), leukemia (MV4-11), lymphoma (HL-60 and P493-6), and neuroblastoma (SK-N-B2) with low-micromolar IC50 values.
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