SIAIS178
| CAS No. | 2376047-73-1 | Cat. No. | BCP34391 |
| Name | SIAIS178 | ||
| Synonyms | SIAIS-178; | ||
| Formula | C50H62ClN11O6S2 | M. Wt | 1012.68 |
| Description | SIAIS178 ist ein potenter und selektiver BCR-ABL-Abbauer auf Basis der PROTAC-Technologie mit einem IC50 von 24 nM. SIAIS178 verursacht einen effektiven Abbau des BCR-ABL-Proteins durch die Rekrutierung von Von Hippel-Lindau (VHL) E3-Ubiquitin-Ligase. | ||
| Pathways | Others Pathway | ||
| Targets | PROTAC | ||
Structure
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