Mizagliflozin

  • Chemical Properties
CAS No. 666843-10-3 Cat. No. BCP35148
Name Mizagliflozin
Synonyms DSP-3235;DSP3235; DSP 3235; KGA-3235; KGA 3235; KGA3235; GSK-1614235; GSK 1614235; GSK1614235;
Formula C28H44N4O8 M. Wt 564.68
  • Biological Activity
Description Mizagliflozin (DSP-3235, KGA-3235, GSK-1614235) is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from that of conventional alpha-glucosidase inhibitors. Mizagliflozin blocks intestinal glucose absorption and reduce GIP secretion in rats and humans, suggesting SGLT1 glucose transport is critical for GIP release.
Pathways Ion Channel/Membrane Transporter GPCR/G Protein 
Targets SGLT 

Structure

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