Mizagliflozin New
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CAS No. | 666843-10-3 | Cat. No. | BCP35148 |
Name | Mizagliflozin | ||
Synonyms | DSP-3235;DSP3235; DSP 3235; KGA-3235; KGA 3235; KGA3235; GSK-1614235; GSK 1614235; GSK1614235; | ||
SMILES | CC1=C(C=CC(=C1)OCCCNCC(C)(C)C(=O)N)CC2=C(NN=C2OC3C(C(C(C(O3)CO)O)O)O)C(C)C | ||
Chemical Name | |||
Formula | C28H44N4O8 | M. Wt | 564.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Mizagliflozin (DSP-3235, KGA-3235, GSK-1614235) is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from that of conventional alpha-glucosidase inhibitors. Mizagliflozin blocks intestinal glucose absorption and reduce GIP secretion in rats and humans, suggesting SGLT1 glucose transport is critical for GIP release. |
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