Prexasertib dimesylate
| CAS No. | 1234015-58-7 | Cat. No. | BCP35489 |
| Name | Prexasertib dimesylate | ||
| Synonyms | LY2606368 dimesylate;LY-2606368 dimesylate;LY 2606368 dimesylate; | ||
| Formula | C20H27N7O8S2 | M. Wt | 557.60 |
| Description | Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti-tumor activity. | ||
| Related Products | 1234015-55-4（Prexasertib mesylate） 1234015-52-1（Prexasertib） 1234015-54-3（Prexasertib dihydrochloride） 1234015-57-6（Prexasertib Mesylate Hydrate） | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Checkpoint | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.