Prexasertib mesylate New
Data Sheet
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| CAS No. | 1234015-55-4 | Cat. No. | BCP40573 |
| Related Products | 1234015-58-7（Prexasertib dimesylate） 1234015-58-7（Prexasertib Mesylate Hydrate） 1234015-54-3（Prexasertib dihydrochloride） 1234015-52-1（Prexasertib） | ||
| Name | Prexasertib mesylate | ||
| Synonyms | LY2606368; LY-2606368; LY 2606368; | ||
| SMILES | COC1=C(C(=CC=C1)OCCCN)C2=CC(=NN2)NC3=NC=C(N=C3)C#N.CS(=O)(=O)O | ||
| Chemical Name | |||
| Formula | C19H23N7O5S | M. Wt | 461.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population. | ||
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