Pico145
CAS No. | 1628287-16-0 | Cat. No. | BCP35558 |
Name | Pico145 | ||
Synonyms | Pico-145; Pico 145; HC-608; HC 608; HC608; | ||
Formula | C23H20ClF3N4O5 | M. Wt | 524.88 |
Description | Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | TRP Channel |
Structure
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