SR-717 free acid
| CAS号 | 2375420-34-9 | 货号 | BCP35922 |
| 中文名 | SR-717 free acid | ||
| 英文名 | SR-717 free acid | ||
| 中文别名 | |||
| 英文别名 | SR 717; SR717; | ||
| 分子式 | C15H9F2N5O3 | 分子量 | 345.26 |
| 生物活性 | SR-717 is an agonist of stimulator of interferon genes STING for treating cancer. SR-717 demonstrates broad interspecies and interallelic specificity. SR-717 functions as a direct cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING. SR-717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant tissues; and facilitated antigen cross-priming. SR-717 also induced the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | STING | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！