Nifurtimox
CAS No. | 23256-30-6 | Cat. No. | BCP36436 |
Name | Nifurtimox | ||
Synonyms | BAY 2502; BAY2502; BAY-2502; Bayer 2502; Bayer2502; Bayer-2502;Lampit; | ||
Formula | C10H13N3O5S | M. Wt | 287.29 |
Description | Nifurtimox is a nitrofuran derivative with antiprotozoal and potential antineoplastic activities. Nifurtimox is reduced by cytosol enzymes or flavin-containing microsomal enzymes to a highly reactive nitro anion free radical; autooxidation of the nitro anion free radical generates cytotoxic superoxide anion (02-). In addition, nifurtimox-derived nitro anion free radicals may alkylate macromolecules such as nucleic acids and proteins, resulting in the disruption of their structure and function. | ||
Pathways | Microbiology/Virology | ||
Targets | Antiparasitics |
Structure
![](https://img.biochemsafebuy.com/uploads/company8/20201108/1604827706_hxzfj.png)
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