Nifurtimox

CAS No.	23256-30-6	Cat. No.	BCP36436
Name	Nifurtimox
Synonyms	BAY 2502; BAY2502; BAY-2502; Bayer 2502; Bayer2502; Bayer-2502;Lampit;
Formula	C10H13N3O5S	M. Wt	287.29

Description	Nifurtimox is a nitrofuran derivative with antiprotozoal and potential antineoplastic activities. Nifurtimox is reduced by cytosol enzymes or flavin-containing microsomal enzymes to a highly reactive nitro anion free radical; autooxidation of the nitro anion free radical generates cytotoxic superoxide anion (02-). In addition, nifurtimox-derived nitro anion free radicals may alkylate macromolecules such as nucleic acids and proteins, resulting in the disruption of their structure and function.
Pathways	Microbiology/Virology
Targets	Antiparasitics

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