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Nifurtimox New
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5.00 g | Get quote | In-stock | Quotation Inquiry |
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CAS No. | 23256-30-6 | Cat. No. | BCP36436 |
Name | Nifurtimox | ||
Synonyms | BAY 2502; BAY2502; BAY-2502; Bayer 2502; Bayer2502; Bayer-2502;Lampit; | ||
SMILES | CC1CS(=O)(=O)CCN1N=CC2=CC=C(O2)[N+](=O)[O-] | ||
Chemical Name | |||
Formula | C10H13N3O5S | M. Wt | 287.29 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Nifurtimox is a nitrofuran derivative with antiprotozoal and potential antineoplastic activities. Nifurtimox is reduced by cytosol enzymes or flavin-containing microsomal enzymes to a highly reactive nitro anion free radical; autooxidation of the nitro anion free radical generates cytotoxic superoxide anion (02-). In addition, nifurtimox-derived nitro anion free radicals may alkylate macromolecules such as nucleic acids and proteins, resulting in the disruption of their structure and function. |
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