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Nifurtimox Chemical Structure

Nifurtimox

Data Sheet For research use only. Not for human use.
Cat. No. :BCP36436CAS No. :23256-30-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 23256-30-6 Cat. No. BCP36436
Name Nifurtimox
Synonyms BAY 2502; BAY2502; BAY-2502; Bayer 2502; Bayer2502; Bayer-2502;Lampit;
SMILES CC1CS(=O)(=O)CCN1N=CC2=CC=C(O2)[N+](=O)[O-]
Chemical Name
Formula C10H13N3O5S M. Wt 287.29
Purity 98% Storage Store at 4-8°C
Description Nifurtimox is a nitrofuran derivative with antiprotozoal and potential antineoplastic activities. Nifurtimox is reduced by cytosol enzymes or flavin-containing microsomal enzymes to a highly reactive nitro anion free radical; autooxidation of the nitro anion free radical generates cytotoxic superoxide anion (02-). In addition, nifurtimox-derived nitro anion free radicals may alkylate macromolecules such as nucleic acids and proteins, resulting in the disruption of their structure and function.
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