CCT-367766
| CAS No. | 2229856-58-8 | Cat. No. | BCP36886 |
| Name | CCT-367766 | ||
| Synonyms | CCT 367766; CCT367766; | ||
| Formula | C49H48ClN7O11 | M. Wt | 946.41 |
| Description | CCT367766 is a potent and the third generation heterobifunctional and PROTAC-based pirin targeting protein degradation probe (PDP), depletes pirin protein expression at low concentration. CCT367766 exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. CCT367766 reveals a good affinity for the recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. CCT367766 provides a potential chemical tool to study a largely unexplored protein. | ||
| Pathways | Others Pathway | ||
| Targets | PROTAC | ||
Structure
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