CCT-367766 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2229856-58-8 | Cat. No. | BCP36886 |
| Name | CCT-367766 | ||
| Synonyms | CCT 367766; CCT367766; | ||
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCOCCOCCN4CCN(CC4)CC5=NC6=C(C=C5)C=C(C=C6)C(=O)NC7=C(C=CC(=C7)NC(=O)C8=CC9=C(C=C8)OCCO9)Cl | ||
| Chemical Name | |||
| Formula | C49H48ClN7O11 | M. Wt | 946.41 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CCT367766 is a potent and the third generation heterobifunctional and PROTAC-based pirin targeting protein degradation probe (PDP), depletes pirin protein expression at low concentration. CCT367766 exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. CCT367766 reveals a good affinity for the recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. CCT367766 provides a potential chemical tool to study a largely unexplored protein. | ||
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